I've come across two very bad glitches, and I don't know if they're fixable or not, but Here they are, and I have had Klepto take a look at these with me as well.
Godwars Glitch. The Boss for the AGS, is composed of "flying rune and adamantite ores". Very hard to describe but definitely needs looking at.
Lunar Magic Glitch. When trying to change to lunar magic, you get froze out of the game and have to restart upon trying to view the lunar spellbook.
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On a side note-
Lesser Demons are distorted.
Barrows Bosses are killable, but no reward is given, it'd be nice to at LEAST recieve some kind of "pk points" for killing them??
Chaos Elemental does not drop anything.